KORELASI ANTARA KENDALI GLUKOSA DAN FUNGSI KOGNISI PASIEN DIABETES MELLITUS TIPE 2 DI MALANG

Sidqi Auzan Mardhi

Abstract


Introduction: Type 2 Diabetes Mellitus (DM) is the most chronic metabolic disease in the world with some chronic complication, one of them is cognitive decline. Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment-Indonesia (MoCA-INA) is frequently used in the world to detect cognitive decline. This research aim to find out correlation between glycemic control and type 2 DM patient cognitive function in Malang.

Method: Method Analytic Observational Study, Cross Sectional study, control group post-test only type with human as its subject amount of 40. Subject chosen based on inclusion criteria, above 40 age, and already had DM for 2-5/5 years. Sample taken is questionnaire data and blood. Questionnaire data interpreted as Normal (N) or Cognitive decline (CD). Blood then sentrifugated, serum used for serum glucose testing. Subject divided in 2 group based on random blood glucose (RBG) and serum blood glucose (SBG), that is controlled glycemic status (CG)(RBG/SBG<200 mg/dL) and uncontrolled glycemic status (UCG) (RBG/SBG>200 mg/dL). Data acquired then analyzed using Spearmann correlation continued with Chi Square and Mann Whitney.

Result:The result of cognitive function testing with MMSE on CG group (N=7,5%, CD=7,5%) whereas on UCG group (N=52,5%, CD=10%). Result of cognitive function testing with MoCA-INA on CG group (N=7,5%, PK=12%) whereas on UCG group (N=5%, CD= 57,5%). Cognitive decline more often found on MoCA-INA than MMSE. However, there is no significance correlation between the 2 variable.

Conclusion: There is no significance correlation between glycemic control and type 2 DM patient cognitive function in Malang

Keywords: Type 2 Diabetes Mellitus, CognitiveDecline, MMSE, MoCA-INA.


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